Nume:                  Ovidiu Alin Ştirban

Data naşterii :      04.05.1974

În:                        Cluj-Napoca  România

 

Pregătire profesională

1981-1989	Scoala germană „George Coşbuc“ Cluj-Napoca
1989-1993	Liceul de informatică din Cluj-Napoca
1993-1999	Studiul Medicinii Umane la Facultatea de Medicină, Iuliu Hatieganu“ Cluj-Napoca
1999-2003	Colaborator ştiinţific la Centrul German de Diabet Düsseldorf, Germania, coordinator al cercetării vasculare
2001-	Inceperea lucării de doctorat în cadrul Universitäţii Heinrich Heine Düsseldorf (Conducătorul lucrării: Prof. Dr. med. Dan Ziegler)
2003-	Medic rezident şi coordonator al cercetării vasculare a Clinicii de Diabet din cadrul Centrului de Cardiologie şi Diabet, Bad Oeynhausen, Germania
Din 01.01.2006	Preşedinte al Asociaţiei Germano-Române pentru cercetarea complicaţiilor Diabetului Zaharat.
Din 01.01.2007	Medic rezident al Clincii de Diabet din cadrul Centrului de Cardiologie şi Diabet NRW, Bad Oeynhausen, Germania
Din august 2007	Membru al prezidiului Federaţiei Internaţionale Danubiebe de Diabet zaharat (Föderation der Internationalen Donau-Symposia über Diabetes mellitus (FID)-Zentraleuropäische Diabetesgesellschaft)

 
Cunoştinţe lingvistice:
Română (limba maternă)
Germană (foarte bine)
Engleză (foarte bine)
Franceză, Italiană (bine)

Activităţi, competenţe:
- Medic rezident al Clincii de Diabet din cadrul Centrului de Cardiologie şi Diabet NRW, Bad Oeynhausen, Germania
- Coordonator al cercetării vasculare a Clinicii de Diabet din cadrul Centrului de Cardiologie şi Diabet NRW, Bad Oeynhausen, Germania
- Investigaţii doppler vasculare periferice si centrale (peste 700 investigaţii)

Teme de cercetare:
- Disfuncţie endotelială
- Efecte cardiovasculare ale alimentelor
- Efecte in vivo ale Advanced Glycation Endproducts şi posibile modalităţi terapeutice

 

Publicatii:

Stirban A, Negrean M, Stratmann B, Gawlowski T, Horstmann T, Gotting C, Kleesiek K, Mueller-Roesel M, Koschinsky T, Uribarri J, Vlassara H, Tschoepe D: Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes. Diabetes Care 2006, 29:2064-2071. (Impact factor: 7,912).

Stirban A, Negrean M. Endotheldysfunktion: Verbindung von Insulinresistenz, Diabetes und Atherosklerose? Diabetes, Stoffwechsel und Herz, 2006,  2: 41-52.

Negrean M, Stirban A, Stratmann B, Gawlowski T, Horstmann T, Götting C, Kleesiek K, Mueller-Roesel M, Koschinsky T, Uribarri J, Vlassara H, Tschoepe D. Effects of low- and high-AGE (Advanced Glycation Endproducts) meals on macro- and microvascular endothelial function and oxidative stress in patients with type 2 diabetes mellitus. The American Journal of Clinical Nutrition, 2007 May;85:1236-43. (Impact factor: 6,56, zugeschrieben nur Prof. Tschöpe).

Kirana S, Stratmann B, Lammers D, Negrean M, Stirban A, Minartz P, Koerperich H, Gastens MH, Götting C, Prohaska W, Kleesiek K, Tschoepe D. Wound therapy with autologous bone marrow stem cells in diabetic patients with ischaemia-induced tissue ulcers affecting the lower limbs. Int J Clin Pract. 2007;61:690-692. (Impact factor: 1,188, zugeschrieben nur Prof. Tschöpe).

Stirban A, Negrean M, Stratmann B, Götting C, Salomon J, Kleesiek K, Tschoepe D. Adiponectin decreases postprandially following a heat processed meal in people with type 2 diabetes mellitus - an effect prevented by benfotiamine and cooking method. Diabetes Care, 2007 August 8 (Epub ahead of print). (Impact factor: 7,912).

Stirban A, Petrule S, Negrean M, Koschinsky T, Tschoepe D. Skin autofluorescence increases postprandially in human subjects. Diabetologia, under second review.

Stirban A, Tschoepe D. Should we be more aggressive in the therapy against cardiovascular risk factors? Should we prescribe statin and aspirin for every diabetic patient? Is it time for polypill? Diabetes Care, 2007 (Review article, accepted, in press). (Impact factor: 7,912).

Stirban A, Tschoepe D. Cardiovascular complications in diabetes  -Targets and interventions - Diabetes Care, 2007 (Review article, accepted, in press). (Impact factor: 7,912).

Uribarri J, Stirban A, Sander D, Cai W, Negrean M, Buenting CE, Koschinsky T, Vlassara H: Single oral challenge by advanced glycation end products acutely impairs endothelial function in diabetic and nondiabetic subjects. Diabetes Care (Accepted, in press: 2007).

Gawlowski T, Stratmann B, Stirban A, Negrean M, Tschoepe D: AGEs and methylglyoxal induce apoptosis and expression of Mac-1 on neutrophils resulting in platelet-neutrophil aggregation. Thromb Res 2007 April 17 (Epub ahead of print)

Stirban A, Negrean A, Götting A, Gawlowski T, Stratmann B, Kleesiek K, Tschöpe D. Dietary advanced glycation end products: in vivo effects on endothelial function and adipokines. Annals of the New York Academy of Science (accepted, in press).

Stirban A, Tschöpe D. Complications of type 1 diabetes – new molecular findings. The Mount Sinai Journal of Medicine. (Invited Review, in process).

 
Invited lectures:

1. Endothelial Dysfunction: Cause or Consequence of Diabetes Mellitus? Jahreskongress der Rumänischen Diabetes-Föderation, Cluj-Napoca, Rumänien, November 2005.
2. Die richtige Küchenpraxis zur Reduzierung krankheitsauslösender
Nahrungs - AGEs und somit Vorbeugung von z.B. Diabeteskomplikationen oder Atherosklerose. GDV FORTBILDUNGSTAGUNG, Bad Sassendorf, März 2006

3. From diabetes to new drugs for cardiovascular prevention ? Kongress der Rumänischen Kardiologie-Gesellschft, Sinaia, Mai 2006.

4. Klinische Bedeutung und Wirkung von PUFA auf die Endothelfunktion beim Hochrisikopatienten. Kongress der Deutschen Gesellschaft für Kardiologie, Mannheim, April 2007.

5. Bedeutung von AGE- induzierten mikro- und makrovaskulären Veränderungen für die Prophylaxe diabetischer Begleiterkrankungen - Rolle des Benfotiamins – Firmensymposium, Frankfurt, April 2007.

6. Nahrungs Advanced Glycation Endproducts: Wirkung auf Endothelzellen und Adipozyten. Jahreskongress der Deutschen Diabetes Gesellschaft, Hamburg, Mai 2007.

7. Dietary advanced glycation end products: in vivo effects on endothelial function and adipokines. 9th International Symposium on the Maillard Reaction, München, September 2006.

8. In vivo Effects of Advanced Glycation End Products. Grand Rounds, Mount Sinai School of Medicine , New York , September 2007.


Reviewer pt.:

                             “Diabetic Medicine”

                             “Diabetologia” (EASD)

                             “Hormone and